• This medicine may cause dangerous fast heartbeats and difficulty breathing. Closely review the section in this leaflet which lists when to call healthcare provider.
• Use tablets by mouth only. Do not misuse this medicine and give by a shot. Does not mix with street drugs.
• If you are taking this medicine to treat drug addiction, you must enroll in a certified treatment program to receive it.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to methadone or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have any of the following conditions: Asthma, intestinal blockage, or severe lung disease.
• Methadone binds to brain receptors, relieving pain. It decreases the feeling of pain and a person's response to pain.
• Take this medicine with or without food. Take with food if it causes an upset stomach.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
• Dispersible tablet: Drop in fruit juice or water. Drink when dissolved.
• A liquid (concentrate, solution) is available if you cannot swallow pills. Mix liquid (concentrate) with 1/4 cup of water before drinking.
• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
Injection:
• This medicine is given as a shot into a muscle, vein, or into the fatty part of the skin.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Many times this medicine is taken on an as needed basis.
• Change in condition being treated. Is it better, worse, or about the same?
• Your healthcare provider will monitor your heartbeat with a test called an ECG.
• Keep a diary of pain control.
• Bowel movements.
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from light.
• Protect tablets from moisture. Do not store in a bathroom or kitchen.
• The injection will be given to you in a healthcare setting. You will not store it at home.
• Throw away any unused medicine by flushing down toilet or sink.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Created: 2006-10-13 14:08:02.0
Modified: 2010-03-22 09:15:16.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• This medicine is used to relieve pain.
• This medicine is used to treat drug addiction and withdrawal.
• This medicine may be habit-forming with long-term use.
• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you have a fast heartbeat, talk with healthcare provider.
• If you have heart disease, talk with healthcare provider.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have thyroid disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Avoid grapefruit and grapefruit juice.
• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.
• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Severe dizziness or passing out.
• Difficulty breathing.
• Fast heartbeat.
• Significant change in thinking clearly and logically.
• Poor pain control.
• Severe nausea or vomiting.
• Severe constipation.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.