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Midodrine Contributions by FoundHealth

Article Revisions

Edited Midodrine Overview: Overview 14 years ago

(MI doe dreen)

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ProAmatine®

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Amatine®; Apo-Midodrine®

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Alpha1 Agonist

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• This medicine is used to treat dangerous low blood pressure.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to midodrine or any part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: High blood pressure when lying down, pheochromocytoma, severe heart disease, trouble urinating, or uncontrolled thyroid gland disease.

• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.

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• Midodrine narrows blood vessels, increasing blood pressure.

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• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Do not lie down after taking this medicine.

• Take last dose of the day at least 4 hours before bedtime.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood pressure and heart rate regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

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Edited Midodrine Overview: 14 years ago

Created: 2007-02-21 09:45:45.0

Modified: 2010-03-25 12:09:56.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat low blood pressure.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• If you have diabetes, talk with healthcare provider.

• If you have heart disease, talk with healthcare provider.

• If you have high blood pressure, talk with healthcare provider.

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before using over-the-counter products that may increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain natural products or supplements.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• High blood pressure.

• Headache.

• Belly pain.

• Skin irritation.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Chest pain or pressure or fast heartbeat.

• Severe dizziness or passing out.

• Severe headache.

• Sudden change in vision.

• Ringing in ears.

• Unable to pass urine.

• Numbness or tingling of hands or feet.

• Any rash.

• No improvement in condition or feeling worse.

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