• If you have an allergy to nitisinone or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• Nitisinone prevents the breakdown of tyrosine. In people with HT-1, harmful chemicals are formed from tyrosine.
• To gain the most benefit, do not miss doses.
• Take this medicine on an empty stomach. Take 1 hour before or 2 hours after meals.
• Swallow capsule whole. Do not chew, break, or crush.
• Capsules can be opened and contents mixed with food or liquid.
• Follow diet plan as recommended by healthcare provider.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Dietary intake of tyrosine and phenylalanine.
• Check blood work regularly. Talk with healthcare provider.
• Follow up with healthcare provider.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Created: 2006-10-13 14:35:19.0
Modified: 2010-04-21 08:17:02.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.
• Hair loss. Hair usually grows back when medicine is stopped.
• Skin irritation.
• Low platelet and white blood cell counts can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Change in skin on hands or feet.
• Sudden change in vision, eye pain, or irritation.
• Significant change in thinking clearly and logically.
• Any rash.
