Side effects
The side effects which may occur with oxycodone use are similar with those that are observed with other opioid analgesics. This includes respiratory depression, apnea, respiratory arrest, circulatory depression, hypotension, or shock.
There are serious side effects associated with oxycodone use. Patients are advised to seek immediate medical attention if any of these side effects occur:
Oxycodone use may also produce less serious side effects including:
Warnings
Before taking this drug, tell your doctor if you have a history of an allergic reaction to any drugs. Oxycodone should be used with caution in some conditions, tell your doctor if you have any of the following health problems:
Oxycodone may be harmful to an unborn baby, and could cause addiction or withdrawal symptoms in a newborn. It can also pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if your are pregnant or breast-feeding a baby.
Oxycodone should be used only by the person it was prescribed for. It should never be shared with another person, especially with those who has a history of drug abuse or addiction. Oxycodone should be kept in a secure place where others cannot get to it.
Do not drink alcohol while on oxycodone therapy. Serious side effects or death can occur when alcohol is taken with narcotic analgesics.
Oxycodone must be taken exactly as prescribed. The patient should tell their doctor if the medicine seems to stop working as it should.
Oxycodone be taken with or without food. Extended release tablets must be swallow whole. Crushing or chewing the tablet leads to rapid release and absorption of a very high dose of oxycodone.
Patients taking oxycodone must be aware that the side effects that may impair their thinking or reactions. They need to be careful driving or doing other activities that require alertness.
Abrupt discontinuation of oxycodone therapy should be avoided to prevent unpleasant withdrawal symptoms.
Contraindications
Oxycontin should not given to patients with known hypersensitivity to oxycodone. It is also contraindicated in situations where opioids are not safe to use this includes respiratory depression and acute or severe bronchial asthma or hypercarbia.
OxyContin should not used if the patient has any of the following conditions:
• Some forms of oxycodone are in a wax matric; you may see this in your stool. The oxycodone has been absorbed but the wax is not.
• This medicine may be habit-forming with long-term use.
• There are two different liquids available, make sure you have the right one.
• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you have a history of drug or alcohol addiction, talk with healthcare provider.
• If you have an enlarged prostate, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have lung disease, talk with healthcare provider. You may be more sensitive to this medicine.
• If you have seizures, talk with healthcare provider.
• If you have thyroid disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.
• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Itching.
• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Severe dizziness or passing out.
• Difficulty breathing.
• Significant change in thinking clearly and logically.
• Poor pain control.
• Severe nausea or vomiting.
• Severe constipation.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.
• Patients receiving this medicine should be monitored for misuse, abuse, and addiction.
• Swallow long-acting tablets whole. Do not chew, break, or crush. Serious reactions can occur if you take broken, chewed, or crushed long-acting tablets.
• This medicine may cause severe liver damage.
Long-acting tablets:
• Please read the medication guide.
• If you have an allergy to oxycodone or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have any of the following conditions: Severe asthma, intestinal blockage, or lung disease.
• Oxycodone binds to brain receptors, relieving pain. It decreases the feeling of pain and a person's response to pain.
• Take this medicine with or without food. Take with food if it causes an upset stomach.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
• Long-acting products: Swallow whole. Do not chew, break, or crush.
• Avoid taking 160 mg tablet with a high-fat meal.
• Do not use long-acting products for immediate pain relief or on an as needed basis.
• A liquid (concentrate, solution) is available if you cannot swallow pills.
• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Many times this medicine is taken on an as needed basis.
• Change in condition being treated. Is it better, worse, or about the same?
• Keep a diary of pain control.
• Bowel movements.
• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.
• Store at room temperature.
• Protect from light.
• Protect capsules and tablets from moisture. Do not store in a bathroom or kitchen.
• Throw away any unused medicine by flushing down toilet or sink.
Created: 2006-10-13 14:47:52.0
Modified: 2010-05-04 10:26:58.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
