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Paclitaxel (Protein Bound) Contributions by FoundHealth

Article Revisions

(pac li TAKS el PROE teen bownd)

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Abraxane®

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Antineoplastic Agent, Antimicrotubular; Antineoplastic Agent, Natural Source (Plant) Derivative; Antineoplastic Agent, Taxane Derivative

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• This medicine is very strong. It can prevent your bone marrow from making some of the cells that your body needs. You will be closely monitored by healthcare provider. Tell healthcare provider right away about any fever, sore throat, signs of infection, bleeding, shortness of breath, or feeling tired.

• There are different brands of this medicine. One brand cannot safely be exchanged for another. Any change must be directed by healthcare provider.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to paclitaxel or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have bone marrow disease.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Paclitaxel (Protein Bound) injures cancer cells causing their death.

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• This medicine is given as a shot into a vein.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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Created: 2005-04-07 17:06:48.0

Modified: 2010-03-09 08:29:13.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat breast cancer.

• This medicine is used to treat lung cancer.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• If you have liver disease, talk with healthcare provider.

• If you have nerve disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Avoid alcohol (includes wine, beer, and liquor).

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Avoid grapefruit and grapefruit juice.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Feeling tired or weak.

• Diarrhea.

• Mouth and lip irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Swelling.

• Hair loss. Hair usually grows back when medicine is stopped.

• Anemia and low white blood cell count.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Muscle pain.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Persistent cough.

• Severe belly pain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Chest pain or pressure.

• Unusual bruising or bleeding.

• Numbness or tingling of hands or feet.

• Not able to eat.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.

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