• If you have an allergy to pemetrexed or any other part of this medicine.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• This medicine is given as a shot into a vein.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Follow up with healthcare provider.
• This medicine will be given to you in a healthcare setting. You will not store it at home.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Created: 2006-10-13 14:54:28.0
Modified: 2010-03-22 14:02:24.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• Take folic acid 1 week before, during, and for 3 weeks after your treatment.
• Your healthcare provider will give you a vitamin B 12 shot 1 week before and every 9 weeks during your treatment.
• Take a medicine that will help prevent a skin rash 3 days during treatment. Talk with healthcare provider.
• If you have kidney disease, talk with healthcare provider.
• Tell dentists, surgeons, and other healthcare providers that you use this medicine.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• Risk of infection. Avoid people with infections, colds, or flu.
• Anemia, low white blood cell count, and low platelet count.
• Feeling tired or weak.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Not hungry.
• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.
• Sore throat.
• Swelling.
• Diarrhea.
• Skin irritation.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Chest pain or pressure.
• Difficulty breathing.
• Severe nausea or vomiting.
• Severe diarrhea.
• Unusual bruising or bleeding.
• Feeling extremely tired or weak.
• Any rash.
• For females, if you become pregnant while taking this medicine.
• No improvement in condition or feeling worse.