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Probenecid Contributions by FoundHealth

Article Revisions

Possible side effects include:

  • Headache
  • Appetite loss
  • Nausea
  • Vomiting
  • Kidney disease (with prolonged use)
  • Kidney stones

Consult your pracitioner before taking any drug if you have:

  • An acute attack of gout
  • Kidney stones or kidney disease
  • Peptic ulcer
  • A blood disorder
  • Cancer

What are the precautions when taking this medicine?

• If you have kidney disease, talk with healthcare provider.

• If you have ulcer disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Avoid alcohol (includes wine, beer, and liquor).

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Flushing.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Not hungry.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.

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Edited Probenecid Overview: Overview 14 years ago

(proe BEN e sid)

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Benuryl™

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Benecid Valdecasas

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Uricosuric Agent

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• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• Do not give this medicine to a child younger than 2 years of age.

• If you have an allergy to probenecid or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have a blood disease or kidney stones.

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• Probenecid reduces uric acid production.

• It increases levels of certain antibiotics.

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• Take this medicine with food to prevent stomach upset.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

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• Change in condition being treated. Is it better, worse, or about the same?

• If you are diabetic, this medicine may interfere with Clinitest®. Use another method of urine glucose testing like Clinistix® or Tes-Tape®.

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

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Edited Probenecid Overview: 14 years ago

Created: 2006-10-27 13:39:44.0

Modified: 2010-03-22 14:07:42.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to prevent gouty arthritis.

• This medicine is used to prevent gout attacks. It may take 6 weeks to see the full effect.

• This medicine is used with certain antibiotics to increase activity against infection.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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