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Propoxyphene and Acetaminophen Contributions by FoundHealth

Article Revisions

(proe POKS i feen & a seet a MIN oh fen)

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Balacet 325™; Darvocet A500®; Darvocet-N® 100; Darvocet-N® 50

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Darvocet-N® 100; Darvocet-N® 50

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Analgesic Combination (Opioid)

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• Tell healthcare provider if you are suicidal or have drug or alcohol abuse. Avoid alcohol or other medicines that slow your actions and reactions.

• Do not take more than the prescribed amount. Serious reactions, including death, may occur.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• Please read the medication guide.

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• If you have an allergy to propoxyphene, acetaminophen, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Intestinal blockage or severe lung disease.

• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.

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• Propoxyphene binds to brain receptors, relieving pain. It decreases the feeling of pain and a person's response to pain.

• Acetaminophen blocks production and release of chemicals that cause pain.

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• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

• Do not take more than prescribed amount. Liver damage can occur.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Many times this medicine is taken on an as needed basis.

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• Change in condition being treated. Is it better, worse, or about the same?

• Keep a diary of pain control.

• Bowel movements.

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• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

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Created: 2005-04-07 17:13:25.0

Modified: 2010-03-09 08:29:06.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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• This medicine is used to relieve pain.

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What are the precautions when taking this medicine?

• This medicine may be habit-forming with long-term use.

• Avoid other sources of acetaminophen. An overdose may cause dangerous problems.

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• If you have lung disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Avoid medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, and other pain medicine.

• Avoid or limit alcohol intake (includes wine, beer, and liquor) to less than 3 drinks a day. Drinking too much alcohol may increase the risk of liver disease.

• Avoid grapefruit and grapefruit juice.

• Be careful if you have G6PD deficiency. Anemia may occur.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Liver damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe dizziness or passing out.

• Difficulty breathing.

• Significant change in thinking clearly and logically.

• Poor pain control.

• Severe nausea or vomiting.

• Feeling extremely tired or weak.

• Yellow skin or eyes.

• Not able to eat.

• Any rash.

• No improvement in condition or feeling worse.

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