• Repaglinide increases insulin secretion from the pancreas and may make tissues more responsive to insulin.
• Metformin reduces sugar production and helps insulin work better.
• Take this medicine 15-30 minutes before meals.
• If a meal is skipped, skip the dose.
• Follow diet plan and exercise program as recommended by healthcare provider.
• Take a missed dose as soon as possible, with a meal.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood sugar as directed by healthcare provider.
• Check blood work (kidney and liver function). Talk with healthcare provider.
• Check weight weekly. Report a weight loss to healthcare provider.
• Have a yearly eye exam and visit to the foot doctor.
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2008-07-23 12:54:36.0
Modified: 2010-03-09 08:22:09.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• Wear disease medical alert identification.
• You should stop this medicine for 2 days after an x-ray with dye.
• Use caution if you are having surgery, if you have a heart attack, severe infection, or stroke, or if you are 80 years of age or older and have not had your kidney function tested.
• If you have lung disease, talk with healthcare provider.
• If you have a weakened heart, talk with healthcare provider.
• Do not drive if blood sugar has been low. There is a greater risk of an accident.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Avoid alcohol (includes wine, beer, and liquor).
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.
• Low blood sugar. Signs include anger, shaking, fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.
• Headache.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Diarrhea.
• Blood acidity (lactic acidosis) may rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Very low blood sugar or very high blood sugar.
• Severe dizziness.
• Difficulty breathing.
• Feeling cold.
• Severe belly pain.
• Severe nausea or vomiting.
• Severe diarrhea.
• Severe muscle pain or weakness.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.
Antidiabetic Agent, Biguanide; Antidiabetic Agent, Meglitinide Derivative; Hypoglycemic Agent, Oral
• A small number of people may develop an acidity to their blood. Metformin can cause this. It may occur in people whose liver or kidneys do not work normally.
• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to repaglinide, metformin, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have any of the following conditions: Acidic blood condition, kidney disease, liver disease, or type 1 diabetes.
