Anti-Parkinson's Agent, MAO Type B Inhibitor; Antidepressant, Monoamine Oxidase Inhibitor
• The desire to harm yourself is a serious symptom of depression. It may last until your depression is completely treated. If you are planning on harming yourself, call the emergency department right away.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• Please read the medication guide.
• If you have an allergy to selegiline or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.
Skin patch:
• If you have pheochromocytoma.
• Fluoxetine should be stopped for at least 5 weeks before starting this medicine.
• Selegiline improves the chemical balance in the brain.
• In depression, sleep and appetite may improve quickly. Other depressive symptoms may take up to 4-6 weeks to improve.
All forms:
• Use this medicine early in the day to avoid sleep problems.
• Follow diet instructions. Certain foods and drinks taken with higher doses of this medicine can cause very dangerous reactions such as sudden high blood pressure. To prevent these problems, get a list of foods to avoid from a nutritionist.
• Oral: Take the capsule or tablet with food.
Oral-disintegrating tablet:
• Place on tongue and let dissolve. Water is not needed. Do not swallow whole. Do not chew, break, or crush.
Skin patch:
• Wash hands before and after use.
• Apply patch to clean, dry, healthy skin on the chest, back, upper leg, or upper arm.
• Move patch site with each patch.
• Use a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not use a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood pressure and heart rate regularly. Talk with healthcare provider.
• Keep a diary of your symptoms.
• Take good care of your teeth. See a dentist regularly.
• Store at room temperature.
• Protect capsules and tablets from moisture. Do not store in a bathroom or kitchen.
• Use oral disintegrating tablets within 3 months of opening pouch.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Created: 2006-10-13 15:38:02.0
Modified: 2010-03-25 12:20:14.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• This medicine is used to treat Parkinson's disease.
• This medicine is used to treat depression.
• If you have been taking this medicine for several weeks, talk with healthcare provider before stopping. You may want to gradually withdraw this medicine.
• If you are taking a high dose (more than 10 mg per day of the capsule or tablet, more than 2.5 mg per day of the oral disintegrating tablet, or more than 6 mg per day of the skin patch) of this medicine, avoid aged meats and cheeses, soy sauce, certain beans, sauerkraut, beer, concentrated yeast extracts, and others. Talk with healthcare provider.
• If you have PKU, talk with healthcare provider. Some products do contain phenylalanine.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• If you are taking this medicine and have high blood pressure, talk with healthcare provider before using over-the-counter products that may increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain natural products or supplements.
• Avoid alcohol (includes wine, beer, and liquor).
• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.
Skin patch:
• Avoid products containing caffeine, phenylalanine, St John's wort, tryptophan, or tyrosine.
• Avoid use of heat sources (such as sunlamps, tanning beds, heating pads, electric blankets, heat lamps, saunas, hot tubs, heated waterbeds). Avoid long, hot baths or sunbathing. Your temperature may rise and cause too much medicine to be released at once.
• The patch may contain conducting metal. Remove patch before MRI.
• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Headache.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Inability to sleep.
• Skin irritation.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• If you are planning to harm yourself or the desire to harm yourself increases.
• Fast heartbeat.
• Severe dizziness or passing out.
• Significant change in thinking clearly and logically.
• Significant change in balance.
• Very nervous and excitable.
• Severe flushing.
• Severe headache.
• Severe nausea or vomiting.
• Severe skin irritation.
• Any rash.
• No improvement in condition or feeling worse.
