Antineoplastic Agent, Tyrosine Kinase Inhibitor; Vascular Endothelial Growth Factor (VEGF) Inhibitor
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to sorafenib or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• Take this medicine on an empty stomach. Take 1 hour before or 2 hours after meals.
• Swallow whole. Do not chew, break, or crush.
• Take this medicine with a full glass of water.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Check blood pressure regularly. Talk with healthcare provider.
• If you are taking a blood thinner, check blood work (prothrombin time/INR). Talk with healthcare provider.
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2006-10-13 15:44:42.0
Modified: 2010-04-06 13:41:26.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• If you have heart disease, talk with healthcare provider.
• If you have had a recent heart attack, talk with healthcare provider.
• If you have high blood pressure, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you are having surgery, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
• Use birth control that you can trust to prevent pregnancy while taking this medicine and for at least 2 weeks after treatment ends.
• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.
• Diarrhea.
• Feeling tired or weak.
• Swelling or pain of hands or feet.
• High blood pressure.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Hair loss. Hair usually grows back when medicine is stopped.
• Not hungry.
• Low white blood cell count or low platelet count.
• Bleeding problems.
• Itching.
• Weight loss.
• Rash.
• Heart disease may rarely occur.
• Holes in the gastrointestinal tract may rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Significant change in thinking clearly and logically.
• Sudden change in vision.
• Chest pain or pressure.
• Severe headache.
• Severe belly pain.
• Severe nausea or vomiting.
• Severe diarrhea.
• Severe swelling or pain of hands or feet.
• Unusual bruising or bleeding.
• Feeling extremely tired or weak.
• Numbness or tingling of hands or feet.
• Any rash.
• No improvement in condition or feeling worse.
