• Serious rashes have been reported. Talk with healthcare provider right away if you develop a rash.
• Tell healthcare provider right away about any fever, sore throat, signs of infection, bleeding, shortness or breath, or feeling tired.
• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• Do not give this medicine to an infant younger than 2 months of age.
• If you have an allergy to pyrimethamine, sulfadoxine, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have a sulfonamide ("sulfa") allergy, talk with healthcare provider.
• If you have anemia caused by low folic acid stores or porphyria.
• If you are breast-feeding.
• To gain the most benefit, do not miss doses.
• Use prescription as directed, even if feeling better.
• Take this medicine with or without food. Take with food if it causes an upset stomach.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Change in condition being treated. Is it better, worse, or about the same?
• If you are taking a blood thinner, check blood work (prothrombin time/INR). Talk with healthcare provider.
• Check blood work regularly. Talk with healthcare provider.
• Store at room temperature.
• Protect from light.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2005-04-07 17:20:06.0
Modified: 2010-03-09 08:24:34.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have seizures, talk with healthcare provider.
• Other protective measures are needed along with this medicine including using screens, bednetting, insect repellent (10% to 35% DEET), and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children. Decrease evening and night-time outdoor activity.
• Be careful if you have G6PD deficiency. Anemia may occur.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
• If you are pregnant or planning on getting pregnant, talk with healthcare provider. You may need even higher doses of folic acid.
• Pregnant females traveling to malaria infested areas should discuss the risks with a healthcare provider first.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Headache.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Belly pain.
• Anemia and low platelet count can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Fever that occurs while in or after return from the malaria area.
• Severe dizziness or passing out.
• Severe nausea or vomiting.
• Dark urine or yellow skin or eyes.
• Unusual bruising or bleeding.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.
