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Tamoxifen Contributions by FoundHealth

Article Revisions

Edited Tamoxifen Overview: Overview 14 years ago

(ta MOKS i fen)

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Apo-Tamox®; Mylan-Tamoxifen; Nolvadex®-D; Novo-Tamoxifen; PMS-Tamoxifen; Tamofen®

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Nolvadex; Tecnofen

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Antineoplastic Agent, Estrogen Receptor Antagonist; Selective Estrogen Receptor Modulator (SERM)

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• This medicine may increase the risk of a stroke, blood clots, and uterine cancer. Talk with healthcare provider.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• Please read the medication guide.

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• If you have an allergy to tamoxifen or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have blood clots or have had blood clots in the past.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Tamoxifen prevents estrogen from feeding estrogen-dependent cancer cells. This decreases spread of the cancer.

• It stimulates ovulation.

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• Take this medicine with or without food. Take with food if it causes an upset stomach.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

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• Change in condition being treated. Is it better, worse, or about the same?

• Periodic breast (monthly self-exam) and regular breast and gynecologic exams are important.

• Bone density test.

• Follow up with healthcare provider.

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• Store at room temperature.

• Protect from light.

• Protect from moisture. Do not store in a bathroom or kitchen.

• Throw away any unused portion of solution 3 months after opening.

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Edited Tamoxifen Overview: 14 years ago

Created: 2005-04-07 17:20:43.0

Modified: 2010-03-09 08:24:17.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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• This medicine is used to reduce the risk of breast cancer in females with increased risk. It may reduce the risk of getting cancer in the other breast after one has cancer.

• This medicine is used to treat breast cancer.

• This medicine is used to cause ovulation.

• This medicine may be given to you for other reasons. Talk with healthcare provider.

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What are the precautions when taking this medicine?

• There may be a higher risk of endometrial or uterine cancer.

• If you have any circulation problems, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid grapefruit and grapefruit juice.

• Limit alcohol intake (includes wine, beer, and liquor).

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Flushing. Wearing layers of clothes or summer clothes and cool environment may help.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Change in sexual ability or desire. This is usually reversible.

• For females, vaginal yeast infection. Report itching or discharge.

• High blood pressure.

• Mood changes.

• Weight loss.

• Feeling tired or weak.

• Sore throat.

• Uterine cancer can rarely occur.

• Stroke and blood clots can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Chest pain or pressure.

• Difficulty breathing.

• Swelling or pain of leg or arm.

• Severe nausea or vomiting.

• Severe diarrhea.

• For females, menstrual changes. These include lots of bleeding, spotting, or bleeding between cycles.

• Weakness, numbness, or tingling.

• Change in strength on one side greater than the other, difficulty speaking or thinking, change in balance, or blurred vision.

• Any rash.

• No improvement in condition or feeling worse.

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