• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to temozolomide, dacarbazine, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
Oral:
• Use prescription as directed, even if feeling better.
• Take this medicine at a similar time of day.
• Take this medicine at bedtime to prevent upset stomach.
• Take this medicine with or without food, but be consistent. Always take with food or always take on an empty stomach.
• Take this medicine with a full glass of water.
• Swallow capsule whole. Do not chew, break, or crush.
• Directions may change depending on blood work results, side effects, and response.
• A liquid is available if you cannot swallow pills. Shake well before use.
• Wear gloves while touching medicine.
• If you vomit after taking this medicine, do not repeat the dose.
Injection:
• This medicine is given as a shot into a vein over a period of time.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
Injection:
• Call healthcare provider for appointment.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Follow up with healthcare provider.
• Store capsules at room temperature.
• Protect capsules from moisture. Do not store in a bathroom or kitchen.
• Store liquid (suspension) in a refrigerator. Throw away any unused portion after 2 months.
• The injection will be given to you in a healthcare setting. You will not store it at home.
Created: 2006-10-13 15:54:11.0
Modified: 2010-08-04 07:37:13.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• This medicine is used to treat brain cancer.
• This medicine is used to treat a variety of cancers.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you are 70 or older or female, use this medicine with caution. You could have more side effects.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• If you are a male and sexually active, protect your partner from pregnancy. Use two forms of birth control that you can trust.
• Risk of infection. Avoid people with infections, colds, or flu.
• Headache.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. You may need a medicine to decrease this side effect. Talk with healthcare provider.
• Swelling.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Diarrhea.
• Hair loss. Hair usually grows back when medicine is stopped.
• Feeling tired or weak.
• Not hungry.
• Low white blood cell count or low platelet count.
• Irritation where the shot is given.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Severe nausea or vomiting.
• Unusual bruising or bleeding.
• Any rash.
• No improvement in condition or feeling worse.
