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Thiotepa Contributions by FoundHealth

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Edited Thiotepa Overview: Overview 14 years ago

(thye oh TEP a)

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Antineoplastic Agent, Alkylating Agent

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• This medicine is very strong. It can prevent your bone marrow from making some of the cells that your body needs. You will be closely monitored by healthcare provider. Tell healthcare provider right away about any fever, sore throat, signs of infection, bleeding, shortness of breath, or feeling tired.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to thiotepa or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Thiotepa injures cancer cells causing their death.

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• The medicine is given as a shot into a vein.

• This medicine may be given into the belly or chest cavities as a wash.

• This medicine is given into the bladder.

• This medicine is given into the spine.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Thiotepa Overview: 14 years ago

Created: 2006-10-13 15:57:49.0

Modified: 2010-06-01 15:50:24.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a variety of cancers.

• This medicine is used as therapy in preparation for bone marrow transplantation.

• This medicine is used to treat cancers which have spread to the brain.

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What are the precautions when taking this medicine?

• If you have bone marrow disease, talk with healthcare provider.

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Anemia, low white blood cell count, and low platelet count.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. You may need a medicine to decrease this side effect. Talk with healthcare provider.

• Hair loss. Hair usually grows back when medicine is stopped.

• Skin irritation.

• Infertility.

• Other forms of cancer can rarely occur later in life.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Feeling extremely tired or weak.

• Severe belly pain.

• Severe nausea or vomiting.

• Significant weight loss.

• Unusual bruising or bleeding.

• Severe skin irritation.

• Any rash.

• No improvement in condition or feeling worse.

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