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Tobramycin (Systemic, Oral Inhalation) Contributions by FoundHealth

Article Revisions

(toe bra MYE sin)

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TOBI®

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TOBI®; Tobramycin Injection, USP

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Antibiotic, Aminoglycoside

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• Injection: This medicine may cause worsening kidney function and hearing loss, and it may change your sense of balance. Talk with healthcare provider.

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• If you have an allergy to tobramycin or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

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• Tobramycin works to injure the bacteria and fight the infection.

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All forms:

• To gain the most benefit, do not miss doses.

• Use prescription as directed, even if feeling better.

• Take this medicine at a similar time of day.

Oral inhalation:

• You will use by inhaling (puffing) through the mouth with a nebulizer machine. Your healthcare provider will teach you proper use.

Injection (I.V.):

• This medicine is given as a shot into a muscle or vein.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

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• Change in condition being treated. Is it better, worse, or about the same?

• Follow up with healthcare provider.

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• Store inhalation (solution) in a refrigerator. Remove each dose from the refrigerator just before using.

• Do not freeze.

• Follow directions for storage of injection. Talk with healthcare provider.

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Created: 2009-12-27 11:25:35.0

Modified: 2010-04-12 14:15:18.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a variety of bacterial infections.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

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What are the precautions when taking this medicine?

• If you have hearing loss, talk with healthcare provider.

• If you have kidney disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

Inhalation solution:

• Abnormal taste. This is usually reversible.

• Cough.

Injection (I.V.):

• Change in hearing can rarely occur.

• Kidney damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Significant change in balance.

• Change in hearing.

• Feeling extremely tired or weak.

• Very nervous and excitable.

• Severe nausea or vomiting.

• Severe diarrhea, even after medicine is stopped.

• Any rash.

• No improvement in condition or feeling worse.

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