• This medicine should be started and restarted in a hospital setting with close monitoring of sodium levels. Serious effects can occur from correcting low sodium levels too fast. Talk with healthcare provider.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• Please read the medication guide.
• If you have an allergy to tolvaptan or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have severe kidney disease or cannot tell when you are thirsty.
• If you have a low sodium level that needs increased right away. Talk with healthcare provider.
• If you are breast-feeding.
• Tolvaptan prevents the kidney from absorbing too much water and causing low sodium levels.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.
• You will be monitored closely by healthcare provider.
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2009-06-05 08:23:53.0
Modified: 2010-03-22 11:24:47.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Read the package insert for more details.
• If you are dehydrated, talk with healthcare provider.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Avoid grapefruit and grapefruit juice.
• Avoid alcohol (includes wine, beer, and liquor).
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Increased thirst.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Feeling tired or weak.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• High blood sugar.
• Mood changes.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Severe dizziness or passing out.
• Severe nausea or vomiting.
• Severe diarrhea.
• Feeling extremely tired or weak.
• Significant change in thinking clearly and logically.
• Difficulty swallowing or speaking.
• Seizures.
• Trouble controlling body movements.
• Unusual bruising or bleeding.
• Unable to pass urine.
• Any rash.
• No improvement in condition or feeling worse.
