• There may be a higher risk of endometrial cancer.
• If you have any circulation problems, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Limit alcohol intake (includes wine, beer, and liquor).
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• Flushing. Wearing layers of clothes or summer clothes and cool environment may help.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• For females, vaginal discharge.
• Endometrial cancer can rarely occur.
• Stroke and blood clots can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Chest pain or pressure.
• Difficulty breathing.
• Swelling or pain of leg or arm.
• Severe nausea or vomiting.
• Severe diarrhea.
• Weakness, numbness, or tingling.
• Change in strength on one side greater than the other, difficulty speaking or thinking, change in balance, or blurred vision.
• Any rash.
• No improvement in condition or feeling worse.
Antineoplastic Agent, Estrogen Receptor Antagonist; Selective Estrogen Receptor Modulator (SERM)
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to toremifene or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• Toremifene prevents estrogen from feeding estrogen-dependent cancer cells. This decreases the spread of cancer.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not use a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Periodic breast (monthly self-exam) and yearly gynecologic exams are important.
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from light.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2005-04-07 17:24:14.0
Modified: 2010-03-09 08:24:19.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
