• Some patients experience severe reactions during the infusion. This medicine causes low blood cell counts for a long period of time. Your healthcare provider will need to monitor your blood cell counts.
• Do not take this medicine if you are pregnant. Use during pregnancy can cause birth defects. If you become pregnant or plan on getting pregnant while taking this medicine, call healthcare provider right away.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to tositumomab, iodine, or any other part of this medicine.
• If you are allergic to mouse proteins, talk with healthcare provider.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• This medicine is given into a vein constantly for a period of time.
• Acetaminophen and diphenhydramine will be given 1 hour before this medicine to decrease fever and chills.
• Medicine to protect the thyroid gland will be given 24 hours before this medicine.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Watch for tarry black stools.
• Follow up with healthcare provider.
• This medicine will be given to you in a healthcare setting. You will not store it at home.
Created: 2005-04-07 17:24:20.0
Modified: 2010-03-09 08:21:34.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• Do not donate blood while using this medicine and for 1 year after stopping.
• If you have kidney disease, talk with healthcare provider.
• If you have thyroid disease, talk with healthcare provider.
• Tell dentists, surgeons, and other healthcare providers that you use this medicine.
• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.
• Follow directions given by healthcare provider after discharge to prevent exposing others to this medicine.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.
• Use birth control that you can trust during treatment and for 12 months after treatment ends.
• If you are a male and sexually active, protect your partner from pregnancy during treatment and for 12 months after treatment ends. Use birth control that you can trust.
• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.
• Risk of infection. Avoid people with infections, colds, or flu.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Headache.
• Anemia, low white blood cell count, and low platelet count.
• Cough.
• Belly pain.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Diarrhea.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Severe dizziness or passing out.
• Severe headache.
• Severe nausea or vomiting.
• Severe diarrhea.
• Unusual bruising or bleeding.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.
