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Vorinostat Contributions by FoundHealth

Article Revisions

Edited Vorinostat Overview: Overview 14 years ago

(vor IN oh stat)

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Zolinza®

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Zolinza®

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Antineoplastic Agent, Histone Deacetylase Inhibitor

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• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to vorinostat or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Vorinostat injures cancer cells causing their death.

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• Take this medicine with food.

• Swallow whole. Do not chew, break, or crush.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• If you are diabetic, you will need to monitor blood sugars closely.

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• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Vorinostat Overview: 14 years ago

Created: 2006-10-11 11:15:30.0

Modified: 2010-03-09 08:31:08.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat skin cancer from lymphoma.

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What are the precautions when taking this medicine?

• If you have had blood clots, talk with healthcare provider.

• If you have diabetes, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling tired or weak.

• Diarrhea.

• Cough.

• Extra muscle activity.

• Not hungry.

• High blood sugar.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Anemia or low platelet count can rarely occur. Medicine may need to be stopped.

• Abnormal taste. This is usually reversible.

• Hair loss. Hair usually grows back when medicine is stopped.

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Swelling.

• Headache.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Chest pain or pressure or fast heartbeat.

• Severe dizziness or passing out.

• Swelling or pain of leg or arm.

• Significant change in thinking clearly and logically.

• Swelling of legs or belly.

• Severe headache.

• Severe nausea or vomiting.

• Severe diarrhea.

• Significant weight loss.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.

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