The effectiveness of Human Menopausal Gonadotropin as an infertility treatment has been confirmed by various clinical trials. One of these studies was done by researchers from the University of Miami School of Medicine. The investigators wanted to find out the effectiveness of Human Menopausal Gonadotropin (hMG) with intrauterine insemination (IUI) for various causes of infertility and to identify the factors that could contribute the successful of the treatment. The participants has infertility problems related to male factor, oligoovulation, tubal or pelvic factor, endometriosis and idiopathic infertility.
Using a retrospective chart analysis, investigators found out that Human Menopausal Gonadotropin (hMG) with intrauterine insemination is effective for some causes of infertility. Data also showed cases of multiple births. Investigators also found out that Human Menopausal Gonadotropin with intrauterine examination did not yield successful results for some patients including those who did not achieve pregnancy get pregnant in three cycles of treatment, females more than 40 years of age, dosage of more than 300 IU daily, and those who had more than 8 mature follicles when hCG was given.
Human Menopausal Gonadotropin (HMG) or menotropins are natural hormones necessary for human reproduction. They are extracted from the urine of post menopausal women. Human Menopausal Gonadotropin is purified and then used as fertility treatment. Each vial of menotropin contains equal amounts of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
Menotropin is a treatment option for women who do not menstruate on their own because of the failure of their pituitary gland to stimulate ovulation. Unlike clomiphene which works by acting on the pituitary gland, hMG and other gonadotrophins promote fertility by directly stimulating the ovaries. Human menopausal gonadotropin products also treat infertility in men with hypo- or normagonadotropic hypogonadism and may be used in combination with hCG to stimulate spermatogenesis.
Menotropin is one of the ovulation drugs often used in Assisted Reproductive Techniques. It may be effective in promoting fertility in women with ovarian dysfunction, endometriosis, and those who have unexplained fertilityno explanation for their struggle to get pregnant.
