There have been some well-designed double-blind, placebo-controlled studies have yielded almost entirely negative results about DMAE's ability to increase a certain type of neurotransmitter, acetylcholine and improve intellectual functioning.1-7 In addition, there is some controversy over whether DMAE really increases acetylcholine at all.8
More DMAE is more widely marketed today as a memory and mood enhancer, DMAE is said to but some believe that it can improve intellectual functioning. The basis for such claims probably stems from its purported ability to increase levels of a neurotransmitter called acetylcholine. Drugs and supplements called cholinergics that increase acetylcholine have been used to treat Alzheimer's disease, tardive dyskinesia, and Huntington's chorea. Because DMAE was believed to be a cholinergic, it has been tried for all of these disorders.
There have been some well-designed double-blind, placebo-controlled studies have yielded almost entirely negative results about DMAE's ability to increase a certain type of neurotransmitter, acetylcholine and improve intellectual functioning.1-7 In addition, there is some controversy over whether DMAE really increases acetylcholine at all.8
DMAE is more widely marketed today as a memory and mood enhancer, but some believe that it can improve intellectual functioning. The basis for such claims probably stems from its purported ability to increase levels of a neurotransmitter called acetylcholine. Drugs and supplements called cholinergics that increase acetylcholine have been used to treat Alzheimer's disease, tardive dyskinesia, and Huntington's chorea. Because DMAE was believed to be a cholinergic, it has been tried for all of these disorders.
There is some evidence that the supplement DMAE (2-Dimethylaminoethanol) may be helpful for ADD, according to studies performed in the 1970s. Two such studies were reported in a review article.1 Fifty children aged 6 to 12 years who had been diagnosed with hyperkinesia (which would likely be ADHD in today's terms) participated in a double-blind study comparing DMAE to placebo. The dose was increased from 300 mg daily to 500 mg daily by the third week and continued for 10 weeks. Evaluations revealed statistically significant test score improvements in the treatment group compared to the placebo group.
Another double-blind study compared DMAE with both Ritalin and placebo in 74 children with "learning disabilities. 1 (It appears that today, the participants would have been given a diagnosis of ADD). The study found significant test score improvement for both treatment groups over a 10-week period.
DMAE (2-dimethylaminoethanol) is a chemical that has been used to treat a number of conditions affecting the brain and central nervous system. Like other such treatments, it is thought to work by increasing production of the neurotransmitter acetylcholine.
There is some evidence that the supplement DMAE (2-Dimethylaminoethanol) may be helpful for ADD, according to studies performed in the 1970s. Two such studies were reported in a review article.1 Fifty children aged 6 to 12 years who had been diagnosed with hyperkinesia (which would likely be ADHD in today's terms) participated in a double-blind study comparing DMAE to placebo. The dose was increased from 300 mg daily to 500 mg daily by the third week and continued for 10 weeks. Evaluations revealed statistically significant test score improvements in the treatment group compared to the placebo group.
Another double-blind study compared DMAE with both Ritalin and placebo in 74 children with "learning disabilities. " 1 (It appears that today, the participants would have been given a diagnosis of ADD). The study found significant test score improvement for both treatment groups over a 10-week period.
There is some evidence that the supplement DMAE (2-Dimethylaminoethanol) may be helpful for ADD, according to studies performed in the 1970s. Two such studies were reported in a review article.1 Fifty children aged 6 to 12 years who had been diagnosed with hyperkinesia (which would likely be ADHD in today's terms) participated in a double-blind study comparing DMAE to placebo. The dose was increased from 300 mg daily to 500 mg daily by the third week and continued for 10 weeks. Evaluations revealed statistically significant test score improvements in the treatment group compared to the placebo group.
Another double-blind study compared DMAE with both Ritalin and placebo in 74 children with "learning disabilities. 1 (It appears that today, the participants would have been given a diagnosis of ADD). The study found significant test score improvement for both treatment groups over a 10-week period.
DMAE (2-dimethylaminoethanol) is a chemical that has been used to treat a number of conditions affecting the brain and central nervous system. Like other such treatments, it is thought to work by increasing production of the neurotransmitter acetylcholine.
