Find us on Social Media:

Share

Valerian Contributions by sshowalter

Article Revisions

More than 200 plant species belong to the genus ValerianaValerian, but the one most commonly used as an herb is Valeriana officinalis.The root of this plant is used for myriad medicinal purposes.

... (more)

More than 200 plant species belong to the genus Valerian, but the one most commonly used as an herb is Valeriana officinalis.The root of this plant is used for myriad medicinal purposes.

... (more)

Our understanding of how valerian might function remains similarly incomplete. Several studies suggest that valerian affects GABA, a naturally occurring amino acid that appears to be related to the experience of anxiety.17-20 Conventional tranquilizers in the Valium family are known to bind to GABA receptors in the brain, and valerian may work similarly. However, there are some significant flaws in these hypotheses, and the reality is that we don't really know how valerian works (or if, indeed, it really does).21,22

... (more)

The herb valerian is best known as a remedy for insomnia. However, because many drugs useful for insomnia also reduce anxiety, valerian has been proposed as an anxiety treatment as well.

... (more)

In a double-blind, placebo-controlled study, 36 people with generalized anxiety disorder were given either valerian extract, valium, or placebo for a period of 4 weeks.8 The study failed to find statistically significant differences between the groups, presumably due to its small size. However, a careful analysis of the results hints, at least, that valerian was helpful.

In addition, a preliminary double-blind study found that valerian may produce calming effects in stressful situations.28 Again, though, this study was too small to provide definitive results.

Another study evaluated the anxiety-relieving effects of a combination containing valerian and lemon balm taken in various doses; some benefits were seen with doses of 600 mg or 1200 mg three times daily, but the highest dose (1800 mg three times daily) actually appeared to increase anxiety symptoms during stressful situations. Furthermore, people taking the herbal treatment at any dose showed slightly decreased cognitive function as compared to those given placebo.

... (more)
  1. Andreatini R, Sartori VA, Seabra ML, et al. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytother Res. 2002;16:650-654.
  1. Kohnen R, Oswald WD. The effects of valerian, propranolol, and their combination on activation, performance and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry. 1988;21:447-448.
... (more)

ses.

More than 200 plant species belong to the genus Valerian, but the one most commonly used as an herb is Valeriana officinalis.The root of this plant is used for myriad medicinal purposes.

... (more)

In a double-blind, placebo-controlled study, 36 people with generalized anxiety disorder were given either valerian extract, valium, or placebo for a period of 4 weeks.8 The study failed to find statistically significant differences between the groups, presumably due to its small size. However, a careful analysis of the results hints, at least, that valerian was helpful.

In addition, a preliminary double-blind study found that valerian may produce calming effects in stressful situations.28 Again, though, this study was too small to provide definitive results.

Another study evaluated the anxiety-relieving effects of a combination containing valerian and lemon balm taken in various doses; some benefits were seen with doses of 600 mg or 1200 mg three times daily, but the highest dose (1800 mg three times daily) actually appeared to increase anxiety symptoms during stressful situations. Furthermore, people taking the herbal treatment at any dose showed slightly decreased cognitive function as compared to those given placebo.

... (more)

The herb valerian is best known as a remedy for insomnia. However, because many drugs useful for insomnia also reduce anxiety, valerian has been proposed as an anxiety treatment as well. It may, therefore, be useful in helping treat panic disorder.

... (more)

The herb valerian is best known as a remedy for insomnia. However, because many drugs useful for insomnia also reduce anxiety, valerian has been proposed as an anxiety treatment as well.

... (more)

The herb valerian is best known as a remedy for insomnia. However, because many drugs useful for insomnia also reduce anxiety, valerian has been proposed as an anxiety treatment as well.

Our understanding of how valerian might function remains similarly incomplete. Several studies suggest that valerian affects GABA, a naturally occurring amino acid that appears to be related to the experience of anxiety.17-20 Conventional tranquilizers in the Valium family are known to bind to GABA receptors in the brain, and valerian may work similarly. However, there are some significant flaws in these hypotheses, and the reality is that we don't really know how valerian works (or if, indeed, it really does).21,22

... (more)

Our understanding of how valerian might function remains similarly incomplete. Several studies suggest that valerian affects GABA, a naturally occurring amino acid that appears to be related to the experience of anxiety.17-20 Conventional tranquilizers in the Valium family are known to bind to GABA receptors in the brain, and valerian may work similarly. However, there are some significant flaws in these hypotheses, and the reality is that we don't really know how valerian works (or if, indeed, it really does).21,22

... (more)
  1. Andreatini R, Sartori VA, Seabra ML, et al. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytother Res. 2002;16:650-654.
  1. Santos MS, Ferreira F, Cunha AP, et al. Synaptosomal GABA release as influenced by valerian root extract—involvement of the GABA carrier. Arch Int Pharmacodyn Ther. 1994;327:220-231.
  1. Santos MS, Ferreira F, Cunha AP, et al. An aqueous extract of valerian influences the transport of GABA in synaptosomes. Planta Med. 1994;60:278-279.
  1. Holzl J, Godau P. Receptor bindings studies with Valeriana officinalis on the benzodiazepine receptor. Planta Medica. 1989;55:642.
  1. Mennini T, Bernasconi P, Bombardelli E, et al. In vitro study on the interaction of extracts and pure compounds from Valeriana officinalis roots with GABA, benzodiazepine, and barbiturate receptors in rat brain. Fitoterapia. 1993;64:291-300.
  1. Santos MS, Ferreira F, Faro C, et al. The amount of GABA present in aqueous extracts of valerian is sufficient to account for [ 3H ] GABA release in synaptosomes. Planta Med. 1994;60:475-476.
  1. Cavadas C, Arajo I, Cotrim MD, et al. In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on GABAa receptor in rat brain. Arzneimittelforschung. 1995;45:753-755.
  1. Kohnen R, Oswald WD. The effects of valerian, propranolol, and their combination on activation, performance and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry. 1988;21:447-448.
... (more)

In a double-blind, placebo-controlled study, 36 people with generalized anxiety disorder were given either valerian extract, valium, or placebo for a period of 4 weeks.16 The study failed to find statistically significant differences between the groups, presumably due to its small size. However, a careful analysis of the results hints, at least, that valerian was helpful.

In addition, a preliminary double-blind study found that valerian may produce calming effects in stressful situations.28 Again, though, this study was too small to provide definitive results. Another study evaluated the anxiety-relieving effects of a combination containing valerian and lemon balm taken in various doses; some benefits were seen with doses of 600 mg or 1200 mg three times daily, but the highest dose (1800 mg three times daily) actually appeared to increase anxiety symptoms during stressful situations. Furthermore, people taking the herbal treatment at any dose showed slightly decreased cognitive function as compared to those given placebo.

... (more)
  1. Andreatini R, Sartori VA, Seabra ML, et al. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytother Res. 2002;16:650-654.
  1. Santos MS, Ferreira F, Cunha AP, et al. Synaptosomal GABA release as influenced by valerian root extract—involvement of the GABA carrier. Arch Int Pharmacodyn Ther. 1994;327:220-231.
  1. Santos MS, Ferreira F, Cunha AP, et al. An aqueous extract of valerian influences the transport of GABA in synaptosomes. Planta Med. 1994;60:278-279.
  1. Holzl J, Godau P. Receptor bindings studies with Valeriana officinalis on the benzodiazepine receptor. Planta Medica. 1989;55:642.
  1. Mennini T, Bernasconi P, Bombardelli E, et al. In vitro study on the interaction of extracts and pure compounds from Valeriana officinalis roots with GABA, benzodiazepine, and barbiturate receptors in rat brain. Fitoterapia. 1993;64:291-300.
  1. Santos MS, Ferreira F, Faro C, et al. The amount of GABA present in aqueous extracts of valerian is sufficient to account for [ 3H ] GABA release in synaptosomes. Planta Med. 1994;60:475-476.
  1. Cavadas C, Arajo I, Cotrim MD, et al. In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on GABAa receptor in rat brain. Arzneimittelforschung. 1995;45:753-755.
  1. Kohnen R, Oswald WD. The effects of valerian, propranolol, and their combination on activation, performance and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry. 1988;21:447-448.
... (more)
  1. Andreatini R, Sartori VA, Seabra ML, et al. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytother Res. 2002;16:650-654.
  1. Santos MS, Ferreira F, Cunha AP, et al. Synaptosomal GABA release as influenced by valerian root extract—involvement of the GABA carrier. Arch Int Pharmacodyn Ther. 1994;327:220-231.
  1. Santos MS, Ferreira F, Cunha AP, et al. An aqueous extract of valerian influences the transport of GABA in synaptosomes. Planta Med. 1994;60:278-279.
  1. Holzl J, Godau P. Receptor bindings studies with Valeriana officinalis on the benzodiazepine receptor. Planta Medica. 1989;55:642.
  1. Mennini T, Bernasconi P, Bombardelli E, et al. In vitro study on the interaction of extracts and pure compounds from Valeriana officinalis roots with GABA, benzodiazepine, and barbiturate receptors in rat brain. Fitoterapia. 1993;64:291-300.
  1. Santos MS, Ferreira F, Faro C, et al. The amount of GABA present in aqueous extracts of valerian is sufficient to account for [ 3H ] GABA release in synaptosomes. Planta Med. 1994;60:475-476.
  1. Cavadas C, Arajo I, Cotrim MD, et al. In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on GABAa receptor in rat brain. Arzneimittelforschung. 1995;45:753-755.
  1. Kohnen R, Oswald WD. The effects of valerian, propranolol, and their combination on activation, performance and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry. 1988;21:447-448.
... (more)

In a double-blind, placebo-controlled study, 36 people with generalized anxiety disorder were given either valerian extract, valium, or placebo for a period of 4 weeks.16 The study failed to find statistically significant differences between the groups, presumably due to its small size. However, a careful analysis of the results hints, at least, that valerian was helpful.

In addition, a preliminary double-blind study found that valerian may produce calming effects in stressful situations.28 Again, though, this study was too small to provide definitive results. Another study evaluated the anxiety-relieving effects of a combination containing valerian and lemon balm taken in various doses; some benefits were seen with doses of 600 mg or 1200 mg three times daily, but the highest dose (1800 mg three times daily) actually appeared to increase anxiety symptoms during stressful situations. Furthermore, people taking the herbal treatment at any dose showed slightly decreased cognitive function as compared to those given placebo.

... (more)

Our understanding of how valerian might function remains similarly incomplete. Several studies suggest that valerian affects GABA, a naturally occurring amino acid that appears to be related to the experience of anxiety.17-20 Conventional tranquilizers in the Valium family are known to bind to GABA receptors in the brain, and valerian may work similarly. However, there are some significant flaws in these hypotheses, and the reality is that we don't really know how valerian works (or if, indeed, it really does).21,22

... (more)

Our understanding of how valerian might function remains similarly incomplete. Several studies suggest that valerian affects GABA, a naturally occurring amino acid that appears to be related to the experience of anxiety.17-20 Conventional tranquilizers in the Valium family are known to bind to GABA receptors in the brain, and valerian may work similarly. However, there are some significant flaws in these hypotheses, and the reality is that we don't really know how valerian works (or if, indeed, it really does).21,22

... (more)
Edited Insomnia and Valerian: History 15 years ago

Valerian's therapeutic use dates back to at lease that time of ancient Greece and Rome. Its medicinal benefits were described by Hippocrates, the father of medicine. In the 2nd century, the Greek physician Galen, alluded the sedative qualities of valerian and prescribed it for insomnia. During the 16th century, valerian was used to relieve a number of symptoms including nervousness, trembling, headaches, and heart palpitations. However, in the mid-19th century, valerian's medicinal properties were held in low regard. At the time, valerian was considered a stimulant that causes some of the symptoms that it was believed to treat. During World War II, valerian was prescribed to relieve symptoms of stress.

... (more)