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Corydalis has not undergone any meaningful safety testing. The herb is known to produce immediate side effects, including nausea and fatigue, in some people. In addition, there are serious safety concerns related to its alkaloid constituent THP. Use of products containing THP has repeatedly been associated with severe and potentially fatal liver injury. 1 2 3 4 5 In addition, there are three reports that use of THP by young children has led to life-threatening suppression of the central nervous system. 6 For these reasons, we strongly recommend against the use of corydalis, especially by young children, pregnant or nursing women, or people with liver disease.
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