Daunorubicin Citrate (Liposomal) Side Effects and Warnings

What are the precautions when taking this medicine?

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• If you have a weakened heart, talk with healthcare provider.

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• If you have had radiation therapy, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

What are some possible side effects of this medicine?

• Feeling tired or weak.

• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.

• Risk of infection. Avoid people with infections, colds, or flu.

• Color of urine is red for 1-2 days after getting medicine.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Hair loss. Hair usually grows back when medicine is stopped.

• Diarrhea.

• Headache.

• Cough.

• Mouth and lip irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Heart damage can rarely occur.

• Anemia, low white blood cell count, and low platelet count.

• Other forms of cancer can rarely occur later in life.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Chest pain or pressure, fast heartbeat, or passing out.

• Difficulty breathing.

• Severe belly pain.

• Unusual burning or tingling sensations.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Severe skin irritation.

• Severe eye irritation.

• Severe swelling.

• Any rash.

• No improvement in condition or feeling worse.