Denileukin Diftitox Side Effects and Warnings

What are the precautions when taking this medicine?

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Not hungry.

• Diarrhea.

• Itching.

• Rash.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Chest pain or pressure, fast heartbeat, or passing out.

• Significant change in thinking clearly and logically.

• Significant weight loss.

• Significant weight gain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Severe swelling.

• Sudden change in vision or in the way you see color.

• Any rash.

• No improvement in condition or feeling worse.