DMAE Side Effects and Warnings

Safety Issues

Although most clinical investigations using DMAE report that the participants experienced no side effects, enough researchers have found adverse reactions to suggest that some caution is appropriate in using this supplement. One study, as noted above, reports increased confusion, drowsiness, and elevated blood pressure; ¹ another reports headache and muscle tension as possible adverse effects; ² and another paper suggests that weight loss and insomnia may accompany use of DMAE. ³ There is also one case report of a woman who developed severe TD after taking DMAE for 10 years for a hand tremor. ⁴ Besides this, a number of manufacturers warn against the use of DMAE by people with epilepsy or a history of convulsions.

Maximum safe dosages for young children, pregnant or nursing women, or people with severe liver or kidney disease have not been established.