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What are the precautions when taking this medicine?
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have had an ulcer or bleeding from your stomach or intestines, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Do not take antacids within 2 hours of this medicine.
• Talk with healthcare provider before using over-the-counter medicines that are used to reduce stomach acid (eg, Pepcid® AC, Prilosec OTC®).
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
• Avoid grapefruit and grapefruit juice.
• Avoid cigarette smoking.
• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
• Use an alcohol-free lotion or cream to help with acne-like skin reactions or dry skin.
• Use birth control that you can trust to prevent pregnancy while taking this medicine and for at least 2 weeks after treatment ends.
What are some possible side effects of this medicine?
• Risk of infection. Avoid people with infections, colds, or flu.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Feeling tired or weak.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Belly pain.
• Eye irritation.
• Skin irritation.
• Lung damage can rarely occur.
Reasons to call healthcare provider immediately
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Difficulty breathing.
• Severe nausea or vomiting.
• Severe diarrhea.
• Unusual bruising or bleeding.
• Dark urine or yellow skin or eyes.
• Not able to eat.
• Persistent cough.
• Feeling extremely tired or weak.
• Unable to pass urine.
• Sudden change in vision, eye pain, or irritation.
• Significant weight loss.
• Severe skin irritation.
• Any rash.
• No improvement in condition or feeling worse.