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Fludarabine
What is it? Overview Usage Side Effects and Warnings
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Fludarabine Overview

Written by FoundHealth.

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U.S. Brand Names

Fludara®; Oforta™

Canadian Brand Names

Fludara®

Mexican Brand Names

Beneflur

Pharmacologic Category

Antineoplastic Agent, Antimetabolite (Purine Antagonist)

What key warnings should I know about before taking this medicine?

• This medicine is very strong. It can prevent your bone marrow from making some of the cells that your body needs. You will be closely monitored by healthcare provider. Tell healthcare provider right away about any fever, sore throat, signs of infection, bleeding, shortness of breath, or feeling tired.

• This medicine may cause certain autoimmune diseases.

• This medicine may cause anemia and low platelet counts.

• Higher doses of this medicine may cause severe side effects. Talk with healthcare provider.

• Do not take this medicine with pentostatin. Serious reactions can occur.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to fludarabine or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

How does it work?

• Fludarabine injures cancer cells causing their death.

How is it best taken?

Injection:

• This medicine is given as a shot into a vein.

Oral:

• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Swallow whole. Do not chew, break, or crush.

• Take this medicine with a full glass of water.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Call healthcare provider for instructions.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

How should I store this medicine?

• The injection will be given to you in a healthcare setting. You will not store it at home.

• Store tablets in original container at room temperature.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2005-04-07 16:42:10.0

Modified: 2010-03-09 08:28:47.0

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