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Fluorouracil (Systemic)
What is it? Overview Usage Side Effects and Warnings
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Fluorouracil (Systemic) Side Effects and Warnings

Written by FoundHealth.

What are the precautions when taking this medicine?

• Avoid alcohol (includes wine, beer, and liquor).

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.

• Apply sunscreen at least 2 hours after taking medicine.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Feeling tired or weak.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Hair loss. Hair usually grows back when medicine is stopped.

• For females, no menstrual cycle.

• Infertility.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Persistent cough.

• Severe belly pain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Not able to eat.

• Severe eye irritation.

• Any rash.

• No improvement in condition or feeling worse.

 
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