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Gonadotropin-Releasing Hormone (GnRH)
What is it? Overview Usage Side Effects and Warnings

What is Gonadotropin-Releasing Hormone (GnRH)?

Side effects and cautions

When given with ovulation-stimulating treatment, GnRH analogues don't cause low-estrogen symptoms. But when taken alone, GnRH analogues may cause a temporary condition which has the same effects as menopause, such as:

  • hot flashes
  • mood swings
  • decreased sexual interest
  • vaginal dryness
  • increased low-density lipoprotein (LDL) cholesterol level
  • decreased high-density lipoprotein (HDL)
  • cholesterol
  • insomnia and
  • headaches.

These side effects will go away when you stop using a GnRH agonist

GnRH antagonist therapy can cause: * nausea or * swelling, redness, or itching at the injection site.