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The Malabar tamarind (from which HCA is extracted) is a traditional food and flavoring in Southeast Asia. No serious side effects have been reported from animal or human studies involving either fruit extracts or the concentrated chemical. A proprietary calcium-potassium salt of HCA appears to have undergone considerable formal safety study, without evidence of toxicity appearing. 1 However, maximum safe doses have not been established, especially for pregnant or nursing women, young children, or people with severe liver or kidney disease.
- Preuss HG, Rao CV, Garis R, Bramble JD, Ohia SE, Bagchi M, Bagchi D. An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight management. J Med. 35(1-6):33-48.