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What are the precautions when taking this medicine?
• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you have diabetes, talk with healthcare provider.
• If you have heart disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.
• Avoid grapefruit and grapefruit juice.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
What are some possible side effects of this medicine?
• Low white blood cell count or low platelet count. Medicine may need to be stopped.
• Feeling tired or weak.
• Hair loss. Hair usually grows back when medicine is stopped.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Belly pain.
• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.
• Not hungry.
• Muscle pain.
Reasons to call healthcare provider immediately
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Difficulty breathing.
• Chest pain or pressure or fast heartbeat.
• Severe nausea or vomiting.
• Severe diarrhea.
• Unusual bruising or bleeding.
• Significant weight gain.
• Dark urine or yellow skin or eyes.
• Feeling extremely tired or weak.
• Numbness or tingling of hands or feet.
• Any rash.
• No improvement in condition or feeling worse.