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Levofloxacin (Systemic)
What is it? Overview Usage Side Effects and Warnings

Levofloxacin (Systemic) Overview

Written by FoundHealth.

(lee voe FLOKS a sin)

U.S. Brand Names


Canadian Brand Names

Levaquin®; Novo-Levofloxacin; PMS-Levofloxacin

Pharmacologic Category

Antibiotic, Quinolone; Respiratory Fluoroquinolone

What key warnings should I know about before taking this medicine?

• This medicine may increase the risk of tendons getting irritated and tearing. The risk is greater in people over the age of 60, heart, kidney or lung transplant patients, or people taking steroid medications. Call healthcare provider right away if you develop pain in the back of the ankle or joint pain or swelling.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• Please read the medication guide.

Reasons not to take this medicine

• If you have an allergy to levofloxacin or any other part of this medicine.

• If you have had tendons get irritated or torn when taking this medicine or a similar medicine in the past.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are breast-feeding.

How does it work?

• Levofloxacin works to injure the bacteria and fight the infection.

How is it best taken?

• To gain the most benefit, do not miss doses.

• Use prescription as directed, even if feeling better.

• Take this medicine at a similar time of day.


• Take tablets with or without food. Take with food if it causes an upset stomach.

• Take liquid (solution) on an empty stomach. Take 1 hour before or 2 hours after meals.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.


• This medicine is given as a shot into a vein over a period of time.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• If you are taking a blood thinner, check blood work (prothrombin time/INR). Talk with healthcare provider.

• Follow up with healthcare provider.

How should I store this medicine?

• Store at room temperature.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

• Follow directions for storage of injection. Talk with healthcare provider.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2009-11-01 18:15:34.0

Modified: 2010-03-15 13:12:13.0

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