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What is it? Overview Usage Side Effects and Warnings

Lignans Usage

Written by FoundHealth.

Therapeutic Uses

A number of preliminary human and animal studies suggest that lignans may be helpful for cancer prevention , particularly of breast and colon cancer, as well reduction of cholesterol. Other highly preliminary research suggests that flaxseeds or lignans may decrease menopausal symptoms 1 and improve kidney function in various types of kidney disease (specifically, lupus nephritis and polycystic kidney disease). 2

Warning: Flaxseed or other treatments for kidney disease should be taken only under a doctor's supervision, due to the serious nature of these disorders.

Despite positive preliminary results in animal studies, 3 studies in humans have yielded mixed results for improving cholesterol levels . 4


  1. Adlercreutz H, Mazur W. Phyto-oestrogens and Western diseases. Ann Med. 29(2):95-120.
  2. Clark WF, Parbtani A, Huff MW, Spanner E, de Salis H, Chin-Yee I, Philbrick DJ, Holub BJ. Flaxseed: a potential treatment for lupus nephritis. Kidney Int. 48(2):475-80.
  3. Prasad K. Dietary flax seed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis. 132(1):69-76.
  4. Hallund J, Ravn-Haren G, B├╝gel S, Tholstrup T, Tetens I. A lignan complex isolated from flaxseed does not affect plasma lipid concentrations or antioxidant capacity in healthy postmenopausal women. J Nutr. 136(1):112-6.


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