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What is it? Overview Usage Side Effects and Warnings

Lutein Side Effects and Warnings

Written by FoundHealth.

Safety Issues

Although lutein is a normal part of the diet, there has not been much evaluation of lutein's safety when taken as a concentrated supplement. One study found evidence that lutein is safe in doses up to the highest tested dose of 10 mg daily. 1 A review of other evidence concluded that long term use of lutein should be safe when taken at a dose of up to 20 mg per day. 2 A 2009 study following 77,126 adults (over age 50), however, suggests that there may be some harm in long-term supplementation with lutein. This study found that long-term use of beta-carotene, lutein or retinol supplements may increase lung cancer risk. Long-term supplement use was determined by subjects' memory of the previous 10 years, so the results of this large study should be interpreted with some caution. 3 Maximum safe dosages for young children, pregnant or nursing women, or those with severe liver or kidney disease have not been established.


  1. Rosenthal JM, Kim J, de Monastario F, et al. Dose-ranging study of lutein supplementation in persons aged 60 years or older. Invest Ophthalmol Vis Sci. 2006;47:5227-5233.
  2. Bahrami H, Melia M, Dagnelie G, et al. Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]. BMC Ophthalmol. 2006 Jun 7. [Epub ahead of print]
  3. Satia JA, Littman A, Slatore CG, Galanko JA, White E. Long-term use of beta-carotene, retinol, lycopene, and lutein supplements and lung cancer risk: results from the VITamins And Lifestyle (VITAL) study. Am J Epidemiol. 169(7):815-28.

1 Comment

Posted 4 years ago

I have used lutein for about 3 months and have urinary irritation. Then found out it contains yeast. Could I have a yeast infection?

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