Mesalamine Side Effects and Warnings

What are the precautions when taking this medicine?

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• If you have PKU, talk with healthcare provider. Some products do contain phenylalanine.

• If you have kidney disease, talk with healthcare provider.

• If you have an inflamed pancreas, talk with healthcare provider.

• If you have an inflamed sac around the heart, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• If you have ulcer disease, talk with healthcare provider.

• The rectal medicine can stain fabric, flooring, painted surfaces, marble, granite, vinyl, and enamel.

• Do not take Apriso™ with antacids.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

What are some possible side effects of this medicine?

• Belly pain.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Headache.

• Sore throat.

• Liver damage can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe belly pain or bloody diarrhea.

• Difficulty breathing.

• Chest pain or pressure.

• If you see tablet bits in the stool.

• Any rash.

• No improvement in condition or feeling worse.