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Methotrimeprazine
What is it? Overview Usage Side Effects and Warnings
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Methotrimeprazine Overview

Written by FoundHealth.

(meth oh trye MEP ra zeen)

Canadian Brand Names

Apo-Methoprazine®; Novo-Meprazine; Nozinan®; PMS-Methotrimeprazine

Mexican Brand Names

Sinogan

Pharmacologic Category

Analgesic, Nonopioid

Reasons not to take this medicine

• Do not give this medicine to a child younger than 2 years of age.

• If you have an allergy to methotrimeprazine, phenothiazines, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Bleeding disorder, severe heart disease, severe liver disease, or seizures.

• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.

How does it work?

• Methotrimeprazine binds to brain receptors, relieving pain. It decreases the feeling of pain and a person's response to pain.

• It affects the vomiting center in the brain.

• It calms the brain.

How is it best taken?

Oral:

• Take this medicine with or without food. Take with food if it causes an upset stomach.

• A liquid (solution) is available if you cannot swallow pills.

Injection:

• This medicine is given as a shot into a muscle, vein, or into the fatty part of the skin.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Keep a diary of pain control.

• Bowel movements.

• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

How should I store this medicine?

• Store at room temperature.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

• The injection will be given to you in a healthcare setting. You will not store it at home.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

Created: 2008-01-16 15:04:12.0

Modified: 2010-03-22 13:32:59.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

 
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