Find us on Social Media:

What is it? Overview Usage Side Effects and Warnings

Metronidazole Overview

Written by FoundHealth.

(met roe NYE da zole)

U.S. Brand Names

Flagyl®; Flagyl® 375; Flagyl® ER; MetroCream®; MetroGel-Vaginal®; MetroGel®; MetroLotion®; Noritate®; Vandazole®

Canadian Brand Names

Apo-Metronidazole®; Flagyl®; Florazole® ER; MetroCream®; Metrogel®; Nidagel™; Noritate®; Trikacide

Mexican Brand Names

Amebidal; Elyzol-S; Epaq; Flagenase; Flagyl; MetroCream; MetroGel; Otrozol; Vertisal

Pharmacologic Category

Amebicide; Antibiotic, Miscellaneous; Antibiotic, Topical; Antiprotozoal, Nitroimidazole

What key warnings should I know about before taking this medicine?

• Metronidazole has been shown to cause cancer in mice and rats. Talk with healthcare provider.

• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to metronidazole or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are less than 12 weeks pregnant.

• If you are breast-feeding.

How does it work?

• Metronidazole works to injure the bacteria and fight the infection.

How is it best taken?

All forms:

• To gain the most benefit, do not miss doses.

• Use prescription as directed, even if feeling better.


• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Take long-acting products on an empty stomach. Take 1 hour before or 2 hours after meals.


• Do not take this medicine by mouth. For skin only. Keep out of mouth, nose, and eyes (may burn).

• Wash hands before and after use.

• Clean affected area before use. Make sure to dry well.

• Apply a thin layer to the affected skin and rub in gently.


• Use gel vaginally.

• Do not have sexual intercourse while using this medicine.

Injection (I.V.):

• This medicine is given as a shot into a vein.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

What should I monitor?

All forms:

• Change in condition being treated. Is it better, worse, or about the same?

Oral and injection:

• If you are taking a blood thinner, check blood work (prothrombin time/INR). Talk with healthcare provider.

How should I store this medicine?

• Store at room temperature.

• Protect capsules and tablets from moisture. Do not store in a bathroom or kitchen.

• Follow directions for storage of injection. Talk with healthcare provider.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2005-04-07 16:59:48.0

Modified: 2010-03-09 08:25:11.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.



No one has made any comments yet. Be the first!

Your Comment