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The safety of motherwort has not been well studied; however, obvious Motherwort side effects appear to be rare. Some people have reported occasional allergic reactions and gastrointestinal distress.
Because of the herb's traditional use for uterine stimulation and the corroborating results of some test tube studies,1 motherwort should not be used by pregnant women until further scientific investigation has been performed.
In addition, preliminary animal evidence suggests that women with a history of breast cancer, or those at high risk for developing it, should avoid motherwort.2 Safety in young children, nursing women, or people with severe liver or kidney disease has not been established.
- "Kong YC, Yeung HW, Cheung YM, et al. Isolation of the uterotonic principle from Leonurus artemisia , the Chinese motherwort. Am J Chin Med. 1976;4:373–382."
- Effects of motherwort ( Leonurus sibiricus L ) on preneoplastic and neoplastic mammary gland growth in multiparous GR/A mice. Anticancer Res. 1992;12:141–144."