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What is it? Overview Usage Side Effects and Warnings

Muromonab-CD3 Overview

Written by FoundHealth.

(myoo roe MOE nab see dee three)

U.S. Brand Names

Orthoclone OKT® 3 [DSC]

Mexican Brand Names

Orthoclone OKT3

Pharmacologic Category

Immunosuppressant Agent; Monoclonal Antibody

What key warnings should I know about before taking this medicine?

• Some patients experience severe reactions during the infusion.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• You will be closely monitored by healthcare provider.

Reasons not to take this medicine

• If you have an allergy to muromonab or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are allergic to mouse proteins, talk with healthcare provider.

• If you have any of the following conditions: Seizures, water in the lungs, or uncontrolled high blood pressure.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

How does it work?

• Muromonab-CD3 helps the body accept a transplanted organ.

How is it best taken?

• This medicine is given as a shot into a vein.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not change dose or stop medicine. Talk with healthcare provider.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Check weight weekly. Report a weight change to healthcare provider.

• For the occurrence of side effects.

How should I store this medicine?

• This medicine will be given to you in a healthcare setting. You will not store it at home.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2006-10-13 14:21:38.0

Modified: 2010-05-03 10:44:14.0

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