Nelarabine Side Effects and Warnings

What are the precautions when taking this medicine?

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• If you have seizures, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Anemia, low white blood cell count, and low platelet count.

• Bruising.

• Bleeding problems.

• Risk of infection. Avoid people with infections, colds, or flu.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Fever.

• Swelling.

• Diarrhea.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Headache.

• Cough.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Seizures.

• Persistent cough.

• Severe nausea or vomiting.

• Severe diarrhea.

• Severe constipation.

• Numbness or tingling of hands or feet.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Difficulty walking.

• Difficulty doing activities of daily living such as doing up buttons or zippers or opening tops of products.

• Any rash.

• No improvement in condition or feeling worse.