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Nicotinamide Adenine Dinucleotide
What is it? Overview Usage Side Effects and Warnings

Nicotinamide Adenine Dinucleotide Usage

Written by FoundHealth.


Effect of Nicotinamide Adenine Dinucleotide on Chronic Fatigue Syndrome (CFS)

Nicotinamide Adenine Dinucleotide supplements have been tried in hopes they might improve energy levels in athletes and in individuals with chronic fatigue, as they work to help with cellular energy...

Read more about Chronic Fatigue Syndrome (CFS) and Nicotinamide Adenine Dinucleotide.

Therapeutic Uses

Two small double-blind, placebo-controlled trials suggest that NADH may be useful for enhancing mental function under conditions of inadequate sleep, such as jet lag . 1 Supplemental NADH has also been proposed as a treatment for Alzheimer's disease , chronic fatigue syndrome , depression , and Parkinson's disease . Additionally, it has additionally been tried as a sports performance enhancer . However, although a few studies have been performed to evaluate these potential uses, 2 3 4 5 6 none were designed in such a way as to produce scientifically meaningful results.


  1. Kay GG, Viirre E, Clark J. Stabilized NADH as a countermeasure for jet lag. Presented at: 48th International Congress of Aviation and Space Medicine; September 17-21, 2000; Rio de Janeiro, Brazil.
  2. Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH)--a new therapeutic approach to Parkinson's disease. Comparison of oral and parenteral application. Acta Neurol Scand Suppl. 146():32-5.
  3. Birkmayer JGD, Birkmayer W. The coenzyme nicotinamide adenine dinucleotide (NADH) as biological antidepressive agent: experience with 205 patients. New Trends Clin Neuropharmacology. 1991;5:19-25.
  4. Birkmayer JG. Coenzyme nicotinamide adenine dinucleotide: new therapeutic approach for improving dementia of the Alzheimer type. Ann Clin Lab Sci. 26(1):1-9.
  5. Forsyth LM, Preuss HG, MacDowell AL, Chiazze L Jr, Birkmayer GD, Bellanti JA. Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome. Ann Allergy Asthma Immunol. 82(2):185-91.
  6. Dizdar N, K├ągedal B, Lindvall B. Treatment of Parkinson's disease with NADH. Acta Neurol Scand. 90(5):345-7.


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