Ofatumumab Side Effects and Warnings

What are the precautions when taking this medicine?

• Hepatitis B testing may be suggested. Unrecognized hepatitis B infection may worsen during treatment.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Serious infections have been reported with use of this medicine. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with healthcare provider.

• Use birth control that you can trust to prevent pregnancy while taking this medicine and for up to 12 months following this medication.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.

• Feeling tired or weak.

• Risk of infection. Avoid people with infections, colds, or flu.

• Diarrhea.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Cough.

• Low white blood cell count or low platelet count.

• Fever, chills, itching, hives, chest pain or pressure, or shortness of breath during infusion.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Significant change in thinking clearly and logically.

• Severe dizziness or passing out.

• Significant change in balance.

• Difficulty breathing.

• Difficulty speaking.

• Feeling extremely tired or weak.

• Severe nausea or vomiting.

• Severe belly pain.

• Yellow skin or eyes.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.