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Pentostatin
What is it? Overview Usage Side Effects and Warnings
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Pentostatin Overview

Written by FoundHealth.

(pen toe STAT in)

U.S. Brand Names

Nipent®

Canadian Brand Names

Nipent®

Pharmacologic Category

Antineoplastic Agent, Antibiotic; Antineoplastic Agent, Antimetabolite (Purine Antagonist)

What key warnings should I know about before taking this medicine?

• This medicine is very strong. It can cause brain, kidney, liver, or lung damage at very high doses. Do not take this medicine with fludarabine. Serious reactions can occur.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to pentostatin or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

How does it work?

• Pentostatin injures cancer cells causing their death.

How is it best taken?

• This medicine is given as a shot into a vein.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Call healthcare provider for appointment.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

How should I store this medicine?

• This medicine will be given to you in a healthcare setting. You will not store it at home.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2005-04-07 16:50:07.0

Modified: 2010-03-09 08:30:07.0

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