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Safety Issues
In general, phosphorus is a safe nutritional substance.
One-time high intake of some forms of phosphate may cause diarrhea. It is also possible that ongoing intake of phosphorus at high levels may impair absorption of copper , iron and zinc . 1 Some evidence hints that excessive consumption of phosphorus in the form of soft drinks might increase kidney stone risk, but study results are contradictory, and if there is an effect it appears to be small. 2 3 Individuals with severe kidney disease should avoid phosphorus supplements, just as they must avoid taking too much of many other minerals.
References
- Bour NJS, Soullier BA, Zemel MB. Effect of level and form of phosphorus and level of calcium intake on zinc, iron, and copper bioavailability in man. Nutr Res 1984;4:371–9.
- Curhan GC, Willett WC, Rimm EB, Spiegelman D, Stampfer MJ. Prospective study of beverage use and the risk of kidney stones. Am J Epidemiol. 143(3):240-7.
- Rodgers A. Effect of cola consumption on urinary biochemical and physicochemical risk factors associated with calcium oxalate urolithiasis. Urol Res. 27(1):77-81.