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What is Plantain Used for Today?
Very weak evidence, too weak to rely upon at all, has been used to indicate that topical plantain is helpful for skin conditions, including poison ivy and eczema . 1 Similarly weak evidence from two studies performed in Bulgaria hint that oral plantain may be helpful for chronic bronchitis . 2 Plantain extracts do appear to have anti-inflammatory effects, at least in the test tube. 3 However, unlike most pharmaceutical anti-inflammatory drugs, which work on the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) systems, one study suggests that plantain may work in a different fashion, by decreasing levels of nitric oxide. 4 Whether this indicates any real potential benefit in people remains unknown.
Other possible actions of plantain constituents based on test-tube studies include anti-cancer effects 5 and anti-viral actions. 6 Contrary to some reports, one study found that plantain does not have diuretic (kidney-stimulating) effects. 7
References
- Duckett S. Plantain leaf for poison ivy. N Engl J Med. 303(10):583.
- Koichev A. Complex evaluation of the therapeutic effect of a preparation from Plantago major in chronic bronchitis. Probl Vatr Med. 1983;11:61–9.
- Vigo E, Cepeda A, Gualillo O, et al. In-vitro anti-inflammatory activity of Pinus sylvestris and Plantago lanceolata extracts: effect on inducible NOS, COX-1, COX-2 and their products in J774A.1 murine macrophages. J Pharm Pharmacol. 2005;57:383–91.
- Vigo E, Cepeda A, Gualillo O, et al. In-vitro anti-inflammatory activity of Pinus sylvestris and Plantago lanceolata extracts: effect on inducible NOS, COX-1, COX-2 and their products in J774A.1 murine macrophages. J Pharm Pharmacol. 2005;57:383–91.
- Galvez M, Martin-Cordero C, Lopez-Lazaro M, et al. Cytotoxic effect of Plantago spp. on cancer cell lines. J Ethnopharmacol. 2003;88:125–30.
- Chiang LC, Chiang W, Chang MY, Ng LT, Lin CC. Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral Res. 2002;55:53–62.
- Doan DD, Nguyen NH, Doan HK, et al. Studies on the individual and combined diuretic effects of four Vietnamese traditional herbal remedies ( Zea mays , Imperata cylindrica , Plantago major and Orthosiphonstamineus ). J Ethnopharmacol. 1992;36:225–31.
