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Safety Issues
Pokeroot is a toxic herb. Ingestion can lead to symptoms such as nausea, vomiting (sometimes with blood), diarrhea, rapid heart rate, a dangerous fall in blood pressure, difficult breathing, confusion, and death. 1 Symptoms may develop with one-time use or insidiously over time. Fresh root is more toxic than dried root. The juice of pokeweed berries is more toxic still, and can cause severe damage to blood cells even when it is only applied to the skin. 2 3 4 Pokeroot should definitely not be used by pregnant or nursing women or young children.
References
- Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press. 1996:215–217.
- FARNES P, BARKER BE, BROWNHILL LE, FANGER H. MITOGENIC ACTIVITY IN PHYTOLACCA AMERICANA (POKEWEED). Lancet. 2(7369):1100-1.
- Barker BE et al. Peripheral blood plasmacytosis following systemic exposure to Phytolacca americana (pokeweed). Pediatrics. 1966;38:490–493.
- Barker BE et al. Mitogenic activity in Phytolacca americana (pokeweed). Lancet. 1965;1:170.
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