Procarbazine Side Effects and Warnings

What are the precautions when taking this medicine?

• If you have diabetes, talk with healthcare provider.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Avoid cigarette smoking.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• If you are a male and sexually active, protect your partner from pregnancy. Use two forms of birth control that you can trust.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. You may need a medicine to decrease this side effect. Talk with healthcare provider.

• Hair loss. Hair usually grows back when medicine is stopped.

• Infertility.

• Other forms of cancer can rarely occur later in life.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Significant change in thinking clearly and logically.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Mouth sores.

• Any rash.

• No improvement in condition or feeling worse.