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The familiar Halloween pumpkin is a member of the squash family, native to North and Central America. The seeds of the pumpkin were used medicinally in Native American medicine, primarily for the treatment of kidney, bladder, and digestive problems. From 1863 to 1936, the United States Pharmacopoeia listed pumpkin seeds as a treatment for intestinal parasites.
In studies, the dose of pumpkin seed oil used for the treatment of BPH was 160 mg three times daily. For the prevention of kidney stones, the dose of pumpkin seed snack tried was 5–10 grams per day.